The Jacksonville Jaguars, led by quarterback Trevor Lawrence, face the Denver Broncos, led by quarterback Bo Nix, on Sunday, Dec. 21, 2025 at Empower Field at Mile High in Denver, Colo.

Where: Empower Field at Mile High, Denver, Colorado (WATCH ON FOX30 Action News Jax When: Sunday, 4:05 p.m. BetMGM NFL odds: Broncos by 3. Against the spread: Jaguars 9-5, Denver 6-7-1. Series record: Broncos lead 8-7,

The Broncos are also in position to clinch the AFC West with a win over the Jags, and a Chargers loss to the Cowboys, who were eliminated from NFC playoff contention with the Eagles’ win over the Commanders on Saturday.

For the Broncos' defense to succeed, they will need their stars to have big games. The Jaguars match up well against this defense in terms of their weapons vs. coverage, but the Broncos have the advantage up front. These five matchups focus on those defensive stars.

The NFL season continues in Week 16 when the Denver Broncos host the Jacksonville Jaguars on Sunday. Start time, how to watch, stream and NFL TV schedule.

Broncos vs. Jaguars radio coverage: Station, channel, streaming to listen live to NFL Week 16 game broadcast originally appeared on The Sporting News. Add The Sporting News as a Preferred Source by clicking here. The red-hot Jacksonville Jaguars will travel to Mile High to face the Denver Broncos in a fierce AFC showdown.

The Broncos officially have a key piece of their front line back for the stretch run.

The veteran defensive lineman has helped Eyioma Uwazurike develop during his first season with a significant role in Denver.

A seasoned Bronco veteran shares specific insights into Bo Nix's "gamer" mentality and his rapid ability to adapt and make crucial plays.