In this portion of the oxyhemoglobin dissociation curve, a relatively small increase in alveolar oxygen tension will produce a relatively large increase in arterial oxygen saturation. Relative ...

The trial demonstrated a significant improvement on the primary endpoint, which was the improvement in the alveolar-arterial oxygen gradient from baseline to week 25. Subjects treated with Leukine ...

Pulmonary gas transfer, measured by percent predicted diffusing capacity of the lung for carbon monoxide (DLco) and alveolar-arterial oxygen gradient (A-aDO2), also demonstrated notable improvement.