image: AAV gene therapy-based genome editing recovered myelination in human CMT1A patient nerve differentiated from iPS cells. view more . Credit: Department of Neuropathology, TMDU ...

The most common CMT subtype is known as CMT1A and is caused by a duplication of the gene encoding peripheral myelin protein 22 (PMP22), leading to high levels of this protein in affected individuals.

New research in mice by Stanford Medicine scientists has found that the process of adaptive myelination, which helps the brain learn new skills, can also promote addiction to opioids.

Myelin plasticity in the ventral tegmental area is required for opioid reward. Nature, 2024; DOI: 10.1038/s41586-024-07525-7; Cite This Page: MLA; APA; Chicago; Stanford Medicine.

PARIS, FRANCE / ACCESSWIRE / March 31, 2021 / Pharnext SA (FR0011191287 - ALPHA) (the 'Company'), an advanced late-stage clinical biopharmaceutical company pioneering new approaches to developing ...

“Myelin development does not complete until we’re in our late 20s or early 30s, which is kind of fascinating,” said Michelle Monje, MD, PhD, a professor of pediatric neuro-oncology at ...

Myelination synchronizes cortical oscillations by consolidating parvalbumin-mediated phasic inhibition. eLife , 2022; 11 DOI: 10.7554/eLife.73827 Cite This Page : ...

The study is published in Nature, in the article, “APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes. “This paper shows very clearly from the snRNAseq of postmortem ...