However, compaction isn't enough. Cells also need to regulate the chromosome structure to enable its function. For example, when genetic information needs to be accessed, the DNA is locally read off.

Abnormalities found in cancer cells include: Translocation. Part of one chromosome has broken off and relocated itself onto another chromosome. Inversion. Part of a chromosome is in reverse order ...

More information: Solmaz Khosravi et al, Epigenetic state and gene expression remain stable after CRISPR/Cas-mediated chromosomal inversions, New Phytologist (2025). DOI: 10.1111/nph.20403 ...

To prepare the 46 chromosomes of a human cell for transport to the daughter cells during cell division, each chromosome forms a compact X-shaped structure with two rod-like copies.

"Clock protein controls daily cycle of gene expression by regulating chromosome loops." ScienceDaily. ScienceDaily, 9 February 2018. <www.sciencedaily.com / releases / 2018 / 02 / 180209131427.htm>.

Chromosomal rearrangements, such as chromosome segment inversions, may affect the epigenetic landscape as well as gene expression. Indeed, different kinds of chromosome segment inversions have ...

The mother's karyotype is 46, XX, inv (9) (q22.1q34.3). Her chromosomes 9 differ in that the #9 with tie inversion has some heterochromatin in the short arm as a normal variant.

A technology developed to detect a chromosome inversion for a rare disease will likely be used to look for similar inversions in other behavioral diseases, such as autism and schizophrenia. By ...

"A new twist: The molecular machines that loop our chromosomes also twist DNA." ScienceDaily. ScienceDaily, 13 December 2024. <www.sciencedaily.com / releases / 2024 / 12 / 241213140624.htm>.