Clemson is coming off a much-needed 24-10 win over Florida State that ended a long home drought against Power 4 opponents. Louisville, on the other hand, is looking to bounce back from a stunning overtime loss to Cal, a game the Cardinals were heavily favored to win.

Clemson vs. Furman will kick off at 4:30 p.m. ET from Memorial Stadium. The game will be televised on The CW, marking the Tigers' first and only appearance on the network this season. Last year, Clemson's Week 13 game against an FCS opponent (The Citadel) was also televised on The CW.

The Furman game is widely viewed as easy win for Clemson and a tune-up for the following week’s Palmetto Bowl game against the Gamecocks in Columbia. Clemson has won 32 games in row against Furman, an FCS school located 45 minutes away in Greenville. The Paladins have not beaten Clemson in 89 years (1936).

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Tyler Venables has been at Clemson since 2020 when Brent Venables was still the Tigers' defensive coordinator.