The behaviour of a receptor protein can be influenced by the presence of certain lipids in the membrane it is embedded in.
Scientists from A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB) have identified why certain lung cancer cells ...
Figure 6: Mechanism of Anti-EGFR resistance in head and neck cancer by activation of TLR4-MyD88 signaling. EGFR inhibition by cetuximab prevents Src activation, thus preventing MyD88 degradation, ...
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A*STAR disarms pathway protecting lung cancer cells

The discovery addresses resistance amongst patients after one to two years of treatment. Researchers at Agency for Science, ...