Previous purification methods, such as ammonium sulphate precipitation, were known to yield a crude purification of proteins. Affinity purification of antibodies is one of widely used techniques where ...

Anion exchange chromatography (AEC) is one of the pillars of downstream processing, especially for IgG purification. Its ability to simultaneously reduce DNA, virus, and host protein contamination has ...

Lactoferrin is a multifunctional protein mainly involved in the immune defense mechanisms against various pathogens. It has been reported that intestinal inflammation was reduced by lactoferrin ...

Affinity chromatography can be applied to a wide array of proteins and works by exploiting the binding properties between proteins and ligands. It involves passing a recombinant protein mixture over a ...

With new upstream bioprocessing technologies continuing to increase yield and product quantities, the pressure for process improvement has fallen firmly on the downstream purification stage. The ...