Immunotherapy has transformed the treatment landscape for non-small cell lung cancer, the most common form of lung malignancy ...

Immune cells often manage to reach head and neck tumors, but once inside, many of them stop doing their job. That paradox has ...

Researchers studying a widely used form of cancer immunotherapy found that certain diets normally associated with weight gain actually helped the treatment work better in mice. The result was ...

In research published in the journal Nature, McGill University researchers looked at the relationship between diet, the gut ...

T-797 enables tumor-cell killing in a human relevant model of checkpoint inhibitor–resistant colorectal cancer liver metastasesNative and ...

Neoadjuvant immune checkpoint blockade (ICB) has shown unprecedented activity in mismatch repair deficient (MMRd) colorectal cancers, but its effectiveness in MMRd endometrial cancer (EC) remains ...

Cancer immunotherapy has historically focused on harnessing the ability of T cells to recognize and attack cancer cells. Adaptive immune checkpoint inhibitors (ICIs) unleash tumor-infiltrating ...

New research has uncovered immune changes in cancer patients that could help identify which patients are most at risk of dangerous heart complications from cancer drugs, known as immune checkpoint ...

When Ana Luisa Perdigoto, MD, PhD, first joined the lab of Kevan Herold, MD, to study type 1 diabetes, patients were just beginning to develop immune checkpoint inhibitor-induced diabetes. As more ...

The answer may lie in what mRNA does inside the immune system. Covid-19 mRNA vaccines deliver genetic instructions that allow ...

Immune cells can reach head and neck tumors, but once there, many stop functioning. This helps explain why immunotherapy with ...