Please provide your email address to receive an email when new articles are posted on . The FDA has approved the supplemental biologics license application for pegloticase, expanding the drug’s label ...

Please provide your email address to receive an email when new articles are posted on . Methotrexate and low-dose prednisone combination allowed complete hair regrowth in up to 31% of patients. Only ...

Greater risks of toxic effects were found at higher methotrexate doses and lower eGFR. Older patients with chronic kidney disease (CKD) starting low-dose methotrexate rather than hydroxychloroquine ...

Patients with hand osteoarthritis (OA) and MRI-detected synovitis who took methotrexate (MTX) 20 mg weekly over a 6-month period had a significant and potentially clinically meaningful reduction in ...

Methotrexate is the mainstay of therapy for the treatment of rheumatoid arthritis (RA) and a number of other inflammatory disorders. It is usually administered orally, but can be given subcutaneously ...

The US Food and Drug Administration (FDA) has approved concomitant use of the biologic pegloticase (Krystexxa) and methotrexate to lower serum uric acid levels (sUA) in patients with chronic gout.

CHICAGO, IL—Low-dose methotrexate, a nonspecific anti-inflammatory agent used for the treatment of rheumatoid arthritis and other autoimmune disorders, failed to prevent cardiovascular events among ...

With overwhelming support from some 200 experts worldwide, dosing of methotrexate (MTX) for psoriasis should start at 15 mg/week for most adults, though lower in those considered "vulnerable" and in ...

High-dose methotrexate (HDMTX) is an antineoplastic dosing strategy used to treat various cancers including primary central nervous system lymphoma. Trimethoprim-sulfamethoxazole (TMP/SMX) is commonly ...

Older patients with chronic kidney disease (CKD) had greater risks for serious adverse events when starting on low-dose methotrexate rather than hydroxychloroquine, a propensity score-matched analysis ...

We previously reported a series of patients treated with high-dose methotrexate (MTX) -based chemotherapy, with or without whole brain radiotherapy. The purpose of this report is to update the initial ...