In Alzheimer's disease, proteins like amyloid beta form clumps, known as plaques, that damage the brain. Subscribe to our ...

UCSF scientists have discovered how microglia engulf and break down amyloid beta, a protein that builds up in Alzheimer's, ...

Microglia, a type of brain immune cell, can gobble up amyloid beta protein, which clumps together into toxic aggregates ...

Scientists at UCSF have uncovered how certain immune cells in the brain, called microglia, can effectively digest toxic ...

Using a microglia-depleting drug and AD mouse models, they identified that microglia have a neuroprotective effect in late disease. However, in early disease, microglia played a key role in spreading ...

To investigate microglia's crucial role in early human brain development, scientists from A*STAR's Singapore Immunology Network (SIgN) led by Professor Florent Ginhoux, utilised cutting-edge ...

SIGLEC 10 identified as a genetic driver for amyloid plaque formation in mice ONC-841 blockade reduced amyloid plaques, normalized microglia function, and improved memory in preclinical Alzheimer’s ...

Early research shows replacing brain immune cells slows a rare brain disease, with potential implications for treating ...

Situated at the intersection of the human immune system and the brain are microglia, specialized brain immune cells that play a crucial role in development and disease. Although the importance of ...

Microglia are specialized immune cells localized to the brain, which mediate neuronal development, maintenance and repair. While their importance is well recognized, these cells “lose almost all ...