DNA aptamer finds novel application in regulating cell differentiation Date: October 10, 2023 Source: Shinshu University Summary: Generating specific cell lineages from induced pluripotent stem ...

Ms. Miyoshi said, "Given our anti-nucleolin DNA aptamer inhibits angiogenesis by inducing VSMC differentiation, it can find applications as a nucleic acid drug for pathological angiogenesis ...

Researchers show that an anti-nucleolin DNA aptamer modulates gene expression and nucleolin localization to determine a cell’s lineage during differentiation Generating specific cell lineages ...

Anti-nucleolin DNA aptamer, iSN04, inhibits angiogenesis. Mouse aortic rings embedded in collagen gel were cultured with or without 30 µM iSN04 for 6 days. Neovascular sprouting, a model of ...

Successful Extension of Nucleic Acid Aptamer Pharmacokinetics in Joint Research by Ajinomoto Co., Inc. and RIBOMIC Inc. Provided by PR Newswire May 6, 2025, 5:00:00 PM ...

The team’s findings published in ACS Applied Materials & Interfaces ("Immunostimulation of Fibrous Nucleic Acid Nanoparticles Can be Modulated through Aptamer-Based Functional Moieties: Unveiling the ...

An aptamer is a short single strand of DNA or RNA that will bind to a specific molecule with high affinity, meaning that it won't bind to molecules other than the one of interest.

AJICAP® Antibody-Drug Conjugate Manufacturing Technology Contributes to Enhanced Efficacy of Antibody DrugsTOKYO, May 6, 2025 /PRNewswire/ -- Ajinomoto Co., Inc. (President: Shigeo Nakamura ...