Ultraviolet (UV) rays from sunlight can cause DNA damage that leads to skin aging and cancer. Fortunately, our bodies have a ...

The researchers developed so-called threofuranosyl nucleic acid (TNA) with a new, additional base pair. These are the first steps on the way to fully artificial nucleic acids with enhanced ...

A base pair is a fundamental unit of double-stranded nucleic acids, such as DNA and RNA. It consists of two complementary nucleobases bound to each other by hydrogen bonds. The base pairing rules ...

DNA is fundamental to the biology of all life on Earth, but how many of us actually know what it is or what it's made of?

Still, 5fC is just as important as the regular base pairs. Researchers used high-resolution mass spectrometry on mice tissue and learned that 5fC is actually present in all of the tissues of the ...

Relevant preliminary work: Stable Cu (I)-Mediated Base Pairing in DNA Jash B, Müller J, Angew. Chem. Int. Ed. 57, 9524-9527 (2018) A metal-mediated base pair that discriminates between the canonical ...

Helicases translocate along their nucleic acid substrates using the energy of ATP hydrolysis and by changing conformations of their nucleic acid–binding sites. Our goal is to characterize the ...

Now, Blokesch's group has discovered the extent of DNA that V. cholerae can steal in a single attack: more than 150,000 nucleic acid base pairs, or roughly 150 genes in one go (the cholera ...

The meeting will focus on pre- and post- transcriptional gene silencing using oligodeoxynucleotides, small interfering RNA, microRNA and other nucleic acid-based molecules to develop effective drugs.

Keystone Symposia: Nucleic Acid Therapeutics: From Base Pairs to Bedsides 10 - 15 January 2012, Santa Fe, New Mexico, United States Introduction The meeting will focus on pre- and post- ...