c-myc is a well-known proto-oncogene encoding for a transcription factor that needs to be tightly regulated in order to preserve cell homeostasis. The Promyelocytic Leukaemia gene product PML plays an ...

Figure 1: Pml-/-mice have accelerated revascularization in response to ischaemia. Figure 2: Pml controls Hif-1α activity and accumulation rate in hypoxic conditions. To exclude further that PML ...

A differential blood count revealed grade 3 lymphocytopenia (Figure 1, and Tables S1 and S2 in the Supplementary Appendix). Retrospective analysis revealed that the lymphocytopenia had reached grade 3 ...