Peutz-Jeghers syndrome (PJS) is an inherited, autosomal dominant disorder characterized by hamartomatous polyps in the gastrointestinal (GI) tract along with pigmented, mucocutaneous lesions.

THE clinical condition described by Peutz,1 of Holland, in 1921 was characterized by him as a remarkable situation of familial polyposis of the mucosa of the small intestine with unusual skin and m ...

Peutz-Jeghers syndrome is also called intestinal polyposis-cutaneous pigmentation syndrome. It is an inherited or sporadic condition characterized by the development of hamartomatouspolyps in the ...

Although Peutz first recognized the combination of pigmented lesions and gastrointestinal polyps in 1921, Jeghers is credited with providing the precise clinical description of the syndrome in 1944. 2 ...

People who suffer from Peutz-Jeghers syndrome, a rare inherited cancer syndrome, develop gastrointestinal polyps and are predisposed to colon cancer and other tumor types. Carefully tracing the ...

Pigmentation Historical. If in several early cases of gastrointestinal polyposis the characteristic pigmentation of the Peutz–Jeghers syndrome may have passed unnoticed, the reverse is certainly ...

Meeting Coverage > DDW Video Capsule Endoscopy Proves Useful in PJS Patients — Peutz-Jeghers Syndrome carries increased risk for bowel neoplasia by Ed Susman, Contributing Writer, MedPage Today ...

LKB1 deficiency in T cells promotes the development of gastrointestinal polyposis. Science, 2018; 361 (6400): 406 DOI: 10.1126/science.aan3975 ...

Peutz–Jeghers syndrome (PJS) is a rare, inherited intestinal polyposis syndrome that is associated with a significantly increased risk of several types of cancer — particularly those of the ...

Peutz–Jeghers syndrome (PJS) is an autosomal dominant disorder characterized by the presence of multiple gastrointestinal polyps and an increased risk for various types of cancers. Inactivating ...

McGill University image: Artist rendition of a growing stomach polyp from a Peutz-Jeghers Syndrome patient. The red cells represent pro-inflammatory T cells that promote polyp development. view more ...