Genes Cancer. 2011 Dec;2 (12):1097-105. 10 Stefan MI, Le Novère N. Cooperative binding. PLoS Comput Biol. 2013;9 (6) ...

Early results from a Phase I clinical trial of AT101, a new CAR T cell therapy that uses a distinct binding mechanism to target CD19, show a 100 percent complete response (CR) rate at the higher ...

More information: Xinyu Wang et al, Aberrant phase separation drives membranous organelle remodeling and tumorigenesis, Molecular Cell (2025). DOI: 10.1016/j.molcel.2025.04.001 ...

Context Therapeutics Inc. Announces Preclinical Data Supporting Unique Binding Mechanism of CT-95 and Progress in Phase 1 Clinical Trial April 30, 2025 — 07:43 am EDT ...

Data from the Phase 1b/2 trial presented at CTAD and more information on the promising mechanism of action of novel antibody TB006 can be found on the TrueBinding website at www.truebinding.com.

PhaseBio initiated REVERSE-IT, a pivotal Phase 3 clinical trial of bentracimab, in March 2020 to support a potential Biologics License Application for bentracimab in both major bleeding and urgent ...