Multipotent stem cells reside in most tissues in the adult body, and can differentiate into a limited range of cell types. Pluripotent stem cells are a step earlier in the tree, able to split into ...

Pluripotent stem cells, as well as placenta and yolk-sac progenitors, can all be grown in vitro. But until the past few years, the goal of culturing totipotent cells in a dish had proved elusive.

BGI Group’s single-cell genomic tools help international research team to convert human pluripotent stem cells to bona fide 8-cell totipotent embryo-like cells Peer-Reviewed Publication BGI Group ...

In a world-first, scientists from BGI-Research, Chinese Academy of Sciences, and a group of partners published a study in Nature, announcing the discovery of a transgene-free, rapid, and ...

Totipotent State Induction The study revealed that a brief 6-hour exposure to 20 nM PlaB effectively activated totipotency-associated genes in mESCs while maintaining pluripotent gene expression.