The Roadrunners fell into a 14-point hole because of two defensive touchdowns, struggling to keep quarterback Owen McCown upright.

Our UTSA vs. South Florida picks, odds & expert predictions expect the Bulls to get whatever they want offensively and win going away on Thursday, November 6.

Preview the Nov. 6 matchup between the South Florida Bulls and UTSA Roadrunners with predictions, odds, over/under, spread, betting lines and more.

USF quarterback Byrum Brown leads Bulls to a dominant win over UTSA in college football Week 11 to improve to 7-2

The Roadrunners are 21-0 in home conference games under Traylor and will tap into that magic once again. Spurred by the sting of a blowout loss at North Texas, UTSA will deliver an upset mirroring last season's win against Memphis, potentially sparking a late-season surge.

After UTSA complicated Tulane’s path to the American Conference championship and College Football Playoff, South Florida is next on the docket. The Bulls cannot afford another loss the rest of the way and hope to keep their chances of potentially representing the Group of 5 in the CFP alive.

The University of Texas at San Antonio is planning to host the Lone Star State’s newest Division I football program to kick off its 2026 season.

The Roadrunners will have plenty of competition for eyes and attendance during Thursday night's meeting with the Green Wave in the Alamodome.