Polyglutamine (polyQ) diseases, a group of dominantly inherited CNS disorders, are caused by an abnormal expansion of cytosine-adenine-guanine repeats (usually over 35-40 repeats). PolyQ diseases, ...
Studies have shown that in ALS patients, microtubules—which are the major component of the cell cytoskeleton and serve as tracks for transporting components from cell bodies to neuronal ...