All living organisms encode the amino acid sequences of proteins as nucleotide sequences (genetic information) in their ...

Children who develop deep wrinkles, stunted growth, and rapidly aging bones and blood vessels as early as 1 to 2 years of age ...

A research team led by Dr. Sun-Uk Kim at the Center for Next-Generation Animal Resources, Korea Research Institute of ...

Scientists have discovered that tRNAs can determine how long mRNAs exist in a cell, causing some messages to be stabilized and translated into more protein, while directing others to be degraded and ...

These are modifiable anticodons, and enable one tRNA to decode several synonymous codons through the wobble effect. The researchers analyzed the translation of I34 in the same protein. They determined ...

News Release 8-Jul-2024 Review paper unveils the potential of suppressor tRNA in gene therapy Peer-Reviewed Publication Science China Press image: (A) Suppressor tRNA readthrough strategy.

TRMT6/61A-dependent base methylation of tRNA-derived fragments regulates gene-silencing activity and the unfolded protein response in bladder cancer. Nature Communications, 2022; 13 (1) DOI: 10. ...

More information: Sophia Zborowsky et al, Adaptive loss of tRNA gene expression leads to phage resistance in a marine Synechococcus cyanobacterium, Nature Microbiology (2025).

A study conducted by a research team from Kumamoto University has shed light on the critical role of a tRNA methylation enzyme, TRMT10A, in supporting brain function. The findings reveal how the ...

To try and fix the mutation, he and his team mutated a human tRNA gene in a phage/ E. coli system to produce a sup-tRNA and injected it into a frog ovary cell carrying a β-thalassemia patient’s mRNA. ...