type 14, has caused several outbreaks of respiratory disease, with considerable morbidity and mortality. Many adenovirus serotypes cause disease in humans: Serotypes 2, 3, and 5 are ubiquitous ...

The Ad5-EBOV vaccine developed in China relies on the recombinant replication-defective human adenovirus type-5 vector to induce immune responses and provide protection against the Ebola virus.

Ad5-CMV-dsRed This recombinant human adenovirus type 5 expresses Discosoma sp. red fluorescent protein (dsRed) under the control of CMV promoter. Ad5-CMV-dsRed serves as a control for other ...

When producing the inhalable vaccine, CanSinoBIO removes genes related to virus replication from the Adenovirus Type 5 Vector, so that the vector is replication-defective in human bodies.