Alpha-1-antitrypsin is a so-called protease inhibitor, a type of enzyme inhibitor. It is produced in the liver but exerts its effects in the lungs, where it regulates immune cell activity. This ...

Alpha-1 antitrypsin deficiency (AATD) is a genetic disorder associated with liver disease, ranging from fibrosis to hepatocellular carcinoma. The disease remains asymptomatic until its final ...

In a nutshell: • Hereditary disease alpha-1-antitrypsin deficiency: researchers have discovered why some patients remain healthy despite a genetic defect, while others develop severe liver ...

About Alpha-1 Antitrypsin Deficiency (AATD) AATD is an inherited genetic disorder that can cause early onset emphysema and liver disease. The most severe form of AATD arises when a patient has a ...

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(RTTNews) - Beam Therapeutics Inc. (BEAM) presented additional data from the Phase 1/2 clinical trial of BEAM-302 in patients with alpha-1 antitrypsin ... mild to moderate liver disease, in ...

a lung and liver disease that is caused by a mutated copy of the SERPINA1 gene, which leads to low levels of the protective alpha-1 antitrypsin (AAT) protein in the blood. AAT is made in the liver ...

Alpha-1-antitrypsin is a so-called protease inhibitor, a type of enzyme inhibitor. It is produced in the liver but exerts its effects in the lungs, where it regulates immune cell activity. This ...