In the microscopic battlefield of plant-microbe interactions, plants are constantly fighting off invading bacteria. New ...

The effects Pulendran’s team found appeared to be mediated by Toll-like receptor 5 (TLR5), a molecule that mediates an immune reaction to flagellin, the protein which forms filamentous bacterial ...

The TLR5 gene, which encodes the receptor for bacterial flagellin, contains a common stop-codon polymorphism that blocks signaling downstream of this receptor. In this paper, Hawn et al.

Nearly half of patients with Crohn's disease (CD) develop selective serum immunoglobulin (Ig)G response to flagellin proteins expressed by bacteria in the Lachnospiraceae family. This study aimed ...

Numerous bacterial adjuvants, most notably lipopolysaccharide, peptidoglycan, flagellin and nonmethylated DNA (CpG motif), can bind selectively to various TLRs on innate immune cells, intestinal ...