For one, microglia hovering around plaques—the type that express the most TREM2—reportedly become desensitized to stimulation ...

Li Hanjie from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences has revealed the presence of microglia in the peripheral nervous system (PNS) and identified ...

In the early stages of spastic paraplegia, the brain appears to play a major role by over-activating the immune system, as ...

Unger was able to nip calcium transients in the bud by injecting a “puff” of sTREM2 into the mouse brain with a pipette; this temporarily silenced nearby neurons, and it did so in wild-type or TREM2 ...

New study links norepinephrine to reduced brain inflammation in Alzheimer’s, offering a potential early treatment target.

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Microglia are very dynamic and constantly extending and retracting processes to explore and monitor the brain. In this image from the new University of Rochester study, white shows the microglial cell ...

By engineering human immune cells called microglia, the researchers have created living cellular 'couriers' capable of responding to brain pathology and releasing therapeutic agents exactly where ...

Microglia are special cells in the human brain. Like a diligent ranger overseeing a forest and dealing with infestations and wildfires, microglia scan the brain environment for germs and initiate ...

New research suggests that calming the brain's immune cells might prevent or lessen the damaging inflammation seen in Alzheimer's disease.

LI Hanjie from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences has revealed the presence of microglia in the peripheral nervous system (PNS) and identified ...