Buffalo Bills, Houston Texans and NFL
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The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 12 on a 48-33 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.
Watching the games will be a blast on Sunday and Monday, but making NFL picks for Week 12, with predictions straight-up and against the spread, has me sweating before we ever get there. 2025 NFL Picks Straight-Up Record: 97-67 (Last Week: 9-6 | 2024 record: 170-96) | ATS Record: 73-90-1 (Last Week: 6-8-1 | 2024 record 147-118-1) Note: All lines are courtesy of FanDuel Sportsbook.