The PNS contains a number of distinct glial cells, each of which is intimately associated with different parts of the neuron or with specific neuronal cell types 94. Neuronal cell bodies in dorsal ...

In the brain, one way that neurons communicate with one another is through secretion of glutamate. Astrocytes, a type of glial cell, mop up extra glutamate, convert it to glutamine—the precursor for ...

These glial products may thereby enhance neuronal excitability and potentiate drug-induced changes at the neuronal sites of action (e.g. dopamine transporter, opioid receptors, etc.) throughout the ...

Kinouchi et al. compared the outcome of retinal neuronal transplantation in wildtype mice with that in mice deficient in glial fibrillary acid protein (GFAP) and vimentin, two proteins that form the ...

Peripheral nerve injury triggers synaptic remodeling. The ganglioside GT1b stabilizes spinal excitatory synapses by ...

“Changes in these genes point to deteriorated neuronal structure and function in many neuronal and glial cell types, as well as increased immune response and inflammation in the brain’s immune ...

We aim to reveal the underlying mechanisms by which the brain adapts to its environment and the role of the neuron-glia interactions in this neuronal plasticity.

forming a Neuron-PNS Microglia-Satellite Glial Cell trio model. This revises the traditional Neuron-Satellite Glial Cell duo model of the PNS based on previous studies in rodent models.

Neuron-glia coculture stained for neuronal Map2 (blue) and pre- and postsynaptic proteins vGlut1 (green) and Homer (red) respectively. Disclaimer: AAAS and EurekAlert! are not responsible for the ...

Research Interests: Pain modulation systems; immune and glial regulation of neuronal function; immune-to-brain communication; glial regulation of pain, opioid analgesia, drugs of abuse, ...