The researchers found that prostate cancer cells are hardwired with a system that allows them to proliferate when the levels of testosterone are very low. But when hormone levels are elevated to ...

Prostate cancer that has become resistant to ... new avenue for treating advanced prostate cancer. The pathway impacts the hormone signaling that drives cancer, but it's not susceptible to the ...

This increase in androgen receptor mRNA and protein was both necessary and sufficient to convert prostate cancer growth from a hormone-sensitive to a hormone-refractory stage, and was dependent on ...

A new study provides the strongest evidence to date on the clinical utility of a polygenic score for prostate cancer ...

Removing EPO signaling in mouse liver tumors leads to tumor regression along with sensitivity to immunotherapy.

The drug is intended for patients with PSMA-positive metastatic castration-resistant prostate cancer (mCRPC) who have received one round of androgen receptor pathway inhibitors (ARPIs), a class of ...

they showed that the same pathway can enhance the growth of some prostate cancer subtypes. "There may be a broader role for FABP5-mTORC1 signaling in other cancer types and even in common chronic ...