Scientific breakthroughs in one disease don't always shed light on treating other diseases. But that's been the surprising ...

More information: Trevor W. Reichman et al, Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes, New England Journal of Medicine (2025). DOI: 10.1056/NEJMoa2506549 ...

Sure enough, the beta cells increased in number by 700% within three months of the treatment. The signs of the disease quickly reversed, and stayed that way even a month after stopping the treatment.

Although all four beta cell types were found during the early to middle stages of type 2 diabetes, their distribution differed from that of mice with normal diets.

In Type 2, beta cell dysfunction has multiple, complex causes, including weight gain, lifestyle changes and lack of exercise. Family history, ethnicity and age can also play a role.

More information: Trevor W. Reichman et al, Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes, New England Journal of Medicine (2025). DOI: 10.1056/NEJMoa2506549 ...

Pancreatic beta-cells synthesize, store and release insulin. But, in type 1 diabetes (T1D), the immune system selectively destroys these cells over time, leading to a lifelong dependence on ...

An estimated 1.6 million Americans have type 1 diabetes, which results from an autoimmune attack that destroys beta cells in the pancreas.

Investigators in Australia have reactivated pancreatic stem cells from a donor with type 1 diabetes (T1D) to become insulin-expressing, showing the possibility that a drug could jump start beta ...