More information: Toomey, Christopher B., Bruch's membrane heparan sulfate retains lipoproteins in the early stages of age-related macular degeneration, Proceedings of the National Academy of ...

A new editorial paper titled "Aging retinal pigmented epithelium: omics-based insights into vision decline" has been ...

Previous models of Bruch's membrane have captured some of its properties but not all. The most common model is a plastic membrane called a Transwell, which supports cell culture in the retina but ...

From hagfish to membrane: Modeling age-related macular degeneration Date: September 13, 2023 Source: Utah State University Summary: Researchers have successfully demonstrated that hagfish slime ...

Professor Elizabeth Vargis and her team study a condition called age-related macular degeneration that causes damage to the retina, making it difficult to see. They study in vitro models, or a model ...

Given that pathological changes in Bruch's membrane have been linked to eye diseases like age-related macular degeneration (AMD), this breakthrough presents an exciting opportunity to potentially ...

"This system shows great potential for development as a substitute Bruch's membrane, providing a synthetic, non-toxic, biostable support for transplantation of the retinal pigment epithelial cells.

This system shows great potential for development as a substitute Bruch's membrane, providing a synthetic, non-toxic, biostable support for transplantation of the retinal pigment epithelial cells.

Using these new techniques. the cell line has been shown to thrive in the 3D environment provided by the scaffolds. “This system shows great potential for development as a substitute Bruch’s membrane, ...

"This system shows great potential for development as a substitute Bruch's membrane, providing a synthetic, non-toxic, biostable support for transplantation of the retinal pigment epithelial cells.

Bruch's membrane (BM) segmentation on optical coherence tomography (OCT) is a pivotal step for the diagnosis and follow-up of age-related macular degeneration (AMD), one of the leading causes of ...