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Burmese pythons will be targeted by hunters for a 10-day period starting on July 11 in the annual Florida Python Challenge.

Alligator Alcatraz, the migrant detention center in the Florida Everglades, is surrounded by swamps infested with massive Burmese pythons.

Florida Python Challenge, July 11-20, 2025, has hunters trying to eliminate invasive Burmese snakes. Do they attack or kill humans? Are they venomous?

As the Florida Python Challenge gets closer, let's take a look at the largest Burmese pythons caught in Florida.