A team from Nashville, Tenn.-based VanderbiltUniversityMedicalCenter has teased out new secrets from Clostridium difficile, the bacterium responsible for many of the ...

Structure of the cell-binding component of the Clostridium difficile binary toxin reveals a di-heptamer macromolecular assembly. Proceedings of the National Academy of Sciences , 2020; 201919490 ...

The C. diff bacteria secrete a toxin that cleaves or cuts itself to generate a fragment that can penetrate cells, damaging them and resulting in a hemorrhagic injury to the gastrointestinal tract.

A newly published paper in PNAS details a research breakthrough that provides a promising starting point for scientists to create drugs that can cure C. diff -- a virulent health care-associated ...

The C. diff toxins can irritate the lower part of the intestines, causing colitis. The colon then swells and becomes inflamed. If this gets bad enough, the intestines can rupture.

A newly published paper in PNAS details a research breakthrough that provides a promising starting point for scientists to create drugs that can cure C. diff—a virulent health care-associated ...

A new study, led by researchers from the University of California, Irvine (UCI), uncovers the long-sought-after, three-dimensional structure of a toxin primarily responsible for devastating ...

C. diff bacteria can produce toxins that damage the gut and lead to various symptoms, including diarrhea and stomach pain.Doctors call this a CDI, and it tends to happen when someone has been ...

C. diff is a bacterium that causes diarrhea, often with severe or even fatal consequences. As part of its growth cycle, C. diff produces two toxins which cause inflammation and damage the lining ...

The Quebec Consortium for Research on C. diff team collected and studied data on more than 5,200 patients from six hospitals in Quebec and Ontario over a 15-month span in 2006 and 2007.

Scientists at Drexel University are putting a twist on the typical approach of vaccination to combat an increasingly common and difficult-to-treat bacterial infection. In hospitals across the country, ...