Researchers at the University Medical Center Göttingen (UMG) have shown how a minimal change in a single ion channel ...

Within the past couple of years, neuroscientists have shown that if the connections between astrocytes and neurons in the hippocampus are disrupted, memory storage and retrieval are impaired.

For a nerve signal to travel across the synapse between two neurons, the axon terminal of the first neuron – the presynaptic neuron – must release chemicals called neurotransmitters into the synaptic ...

Calcium Signaling: The first clue about the possible connection between brain and muscle cells came when Janelia scientists noticed something strange about the endoplasmic reticulum, or ER - the ...

The paper S.S.H. Wang et al., “Fusion competent synaptic vesicles persist upon active zone disruption and loss of vesicle docking,” Neuron, 91:777-91, 2016. Hair trigger Neurons send each other ...

Calcium regulation is fundamental to the function of all cells, including neurons. It plays a crucial role in signal transmission, particularly in the presynaptic area where native aSN is typically ...

But how do brain cells send messages? The first step in this messaging process is the action potential, or a wave of electricity triggered in the nerve cell, or neuron.The neurons found in the ...

The electrically charged calcium causes vesicles to “fuse” to the outer membrane of presynaptic neurons, releasing their communicative chemical cargo to the postsynaptic cell.

“A lot of research has focused on calcium signaling in dendrites – the sites where neurons receive signals from other neurons. Calcium signaling in the cell body of neurons has received less attention ...

There was no effect of this late Rac1 deletion on presynaptic neuron viability (Figure 4—figure supplement 1A–B). Figure 4 with 3 supplements see all. ... a high-frequency train of action potentials ...

In summary, these results demonstrate that Wnt5a is not required for dendritic spine formation during development, possibly due to compensation by other Wnts including Wnt7a. However, Wnt5a is ...