Enzymes are vital to metabolism and drive countless biological processes in humans, plants, and industry. Yet, when ...

Recently, a collaborative research team led by Professor Yong-Qiang Li of Shandong University and Professor Yanmei Yang of ...

A research team has successfully engineered a novel PET hydrolase enzyme, PET2-21M, achieving a remarkable improvement in the ...

Trapping Conformational States Along Ligand-Binding Dynamics of Peptide Deformylase: The Impact of Induced Fit on Enzyme Catalysis. PLoS Biology , 2011; 9 (5): e1001066 DOI: 10.1371/journal.pbio ...

(a,b) Twenty-nine box plots of the distributions of binding energies for the complexes between each of the 29 enzymes in the reduced data set and each of 125 metabolites (docking experiments) (a ...

High-resolution cryo-electron microscopy makes it possible to study complex enzymatic processes in detail. With this method, ...

Tunable biomimetic foldamers appeal more to non-sequence-specific DNA-binding enzymes than do real DNA molecules, suggesting a new way to interfere with HIV and other viruses ...

Additional experiments used GnT-IVa enzymes with different N-glycans capable of binding the GnT-IVa lectin domain: one with oligomannose (weak binding) and another with GlcNAc (strong binding).

In their important manuscript, Gangadharan, Kober and Rice focus on how Stu2/XMAP215-family microtubule polymerases use their TOG domains to catalytically promote microtubule growth, testing whether ...

An example of high-capacity binding of enzymes to nonmodified Amberlite IRC50 resin is shown in the Figure. Here, two different enzymes are bound to IRC50 using buffered conditions at a pH of 7.3 ...

Mugridge explained that if the team can grow crystals of the proteins in complex with the modified RNA groups that they act on, they can take them to a national lab and shoot them with high-intensity ...