UCSF researchers have identified ADGRG1, a microglial receptor that helps clear amyloid beta plaques in Alzheimer’s disease.

Without the receptor, ADGRG1, the microglia barely nibbled on the toxic protein. Using a mouse model of Alzheimer's disease, ...

Microglia, a type of brain immune cell, can gobble up amyloid beta protein, which clumps together into toxic aggregates ...

Without the receptor, ADGRG1, the microglia barely nibbled on the toxic protein. Using a mouse model of Alzheimer’s disease, the researchers observed how the loss of ADGRG1 led to the rapid buildup of ...

Scientists at UCSF have uncovered how certain immune cells in the brain, called microglia, can effectively digest toxic ...

UCSF scientists have discovered how microglia engulf and break down amyloid beta, a protein that builds up in Alzheimer's, ...

In Alzheimer's disease, proteins like amyloid beta form clumps, known as plaques, that damage the brain.But in some people, ...

SIGLEC 10 identified as a genetic driver for amyloid plaque formation in mice ONC-841 blockade reduced amyloid plaques, normalized microglia function, and improved memory in preclinical Alzheimer’s ...

De Strooper has received numerous honors, including the Zenith Fellows award from the Alzheimer’s Association in 2017 and the Brain Prize in 2018. He holds more than 20 patents, founded two biotech ...

AB Science receives several European countries approval to initiate the confirmatory phase 3 study of masitinib in ALS: Paris Saturday, July 26, 2025, 18:00 Hrs [IST] AB Science S ...

Exercise wisely. If you like to exercise outside, walk or workout in parks or open spaces away from traffic or at least in ...

Troculeucel, a cryopreserved autologous, non-genetically modified NK cell product, appears to cross the blood brain barrier (BBB) via CXCR3, to reduce neuroinflammation via a simple IV administration.