Marcotrigiano (from left), Rice, Dentzer, and Lorenz, posing with Sadie the black lab, found some surprises in the structure of hepatitis C virus's NS2-3 protease.

The team presented the three-dimensional structure of SENP5 in complex with different types of SUMO. The results of the analysis of the different complexes reveal a positively charged region that ...

Figure 1: Overall structure of serpin-protease complex and comparison with other serpins. Figure 2: Stereo diagram showing the RCL between P4 and P4′ in the electron density and interactions ...

Some of the mystery has been solved with the publication last month of the first high-resolution crystal structure of an intramembrane protease. Yongchen Wang, Yingjiu Zhang, and Ya Ha from Yale ...

Crystal structure of SARS-CoV-2 main protease (Mpro) in complex with a Chinese herb inhibitor shikonin. a Chemical structure of the non-colavent inhibitor shikonin. b Structure of Mpro dimer.

Among Atg4-family proteases, crystallographic studies have been limited to Homo sapiens (Hs) Atg4A and HsAtg4B. The first reported structure was HsAtg4B, whose structure is composed of the two ...

A research led by the IBB-UAB has managed to decypher the structure of the human protease SENP5, implicated in neurodegenerative disorders, cardiovascular diseases and the development of cancer.

Crystal structure of SARS-CoV-2 papain-like protease. Compuscript Ltd. Journal Acta Pharmaceutica Sinica B DOI 10.1016/j.apsb.2020.08.014 ...

Foldit players demonstrate that human spatial awareness can outsmart computers in modeling simian AIDS-causing virus. It took the online gaming community just three weeks to solve the structure of ...

SHANGHAI, April 10 (Xinhua) -- Chinese researchers have determined the high-resolution crystal structure of the main protease (Mpro) from the COVID-19 virus and identified drugs that may have promise ...

Get Instant Summarized Text (Gist) The three-dimensional structure of the human protease SENP5, involved in post-translational SUMOylation, has been determined in complex with various SUMO types.