A proposed Interstate 66 TransAmerica Corridor could revitalize Southeast Missouri by connecting rural communities to jobs, ...

A heat advisory will be in effect for Southeast Missouri next week, with heat indexes expected to top 110 degrees. Both rural ...

Six students from the Jacksonville area are recognized for academic achievement at Southeast Missouri State University.

The Missouri Department of Conservation will host a hike of Civil War locations in southeast Missouri on July 23.

Donations of $5 or more will be accepted at the door in support of the Arts Council of Southeast Missouri. Director Kelly Downes said it will fund a variety of projects.

SOUTHEAST Mo. (KFVS) - The U.S. Geological Survey recorded two small earthquakes in southeast Missouri on Thursday night, ...

The Cape Girardeau Police Department in southeast Missouri said Thursday it had no updates on the search for a 32-year-old Kansas City man who has been missing since Saturday.

The first home Missouri basketball game in the 2025-26 season is set. Here’s who MU will face to open its home account, and when it will face Minnesota.

The Cape Girardeau Police Department in southeast Missouri said Thursday it had no updates on the search for a 32-year-old Kansas City man who has been missing since Saturday.

We had the opportunity to speak with Southeast Missouri State University's incoming president, Dr. Brad Hodson.