Shares in AbbVie have slumped after a pair of failed phase 2 trials for emraclidine, a schizophrenia drug it acquired as part of its $8.7 billion takeover of Cerevel Therapeutics last year.
AbbVie’s ABBV mid-stage studies of emraclidine for schizophrenia failed to meet their primary endpoint. Shares of the company lost 12.6% on Monday in response to the disappointing news.
However, Cerevel's schizophrenia drug emraclidine unexpectedly failed its clinical trials, raising severe doubts that AbbVie will get much return on that nearly $9 billion investment. It's not ...
Neurocrine's drug acts as a muscarinic M4 selective agonist, while KarXT targets M1 and M4 receptors and emraclidine is described as a muscarinic M4 receptor-positive allosteric modulator (PAM).
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