Engineering a Biomimetic In Vitro Model of Bruch’s Membrane Using Hagfish Slime Intermediate Filament Proteins. ACS Biomaterials Science & Engineering , 2023; 9 (8): 5051 DOI: 10.1021 ...

VIENNA, Austria — A laser treatment that "cleans up" Bruch's membrane and therefore rejuvenates the retina could slow disease progression in various forms of maculopathy and may prevent age ...

A new editorial paper titled "Aging retinal pigmented epithelium: omics-based insights into vision decline" has been ...

They study in vitro models, or a model developed in a laboratory setting, of Bruch’s membrane, a layer in the retina of the eye, to compare the natural aging process to the effects of AMD.

Retinal Structures Affected in AMD. In the retina, age-related macular degeneration (AMD) affects the complex of photoreceptors, retinal pigment epithelium (RPE), Bruch’s membrane (BM) and the ...

AMD can be caused by changes in the Bruch's membrane, ... Retinal pigment epithelial cells can be cultured on fluocinolone acetonide treated nanofibrous scaffold.

Scientists have found a way to use nanotechnology to create a 3D "scaffold" to grow cells from the retina ... "This system shows great potential for development as a substitute Bruch's membrane, ...

The eye's outer blood-retina barrier comprises retinal pigment epithelium, Bruch's membrane and the choriocapillaris. Image credit: National Eye Institute. Bharti and colleagues combined three ...

This system shows great potential for development as a substitute Bruch's membrane, providing a synthetic, non-toxic, biostable support for transplantation of the retinal pigment epithelial cells.

AMD can be caused by changes in the Bruch’s membrane, which supports the RPE cells, and breakdown of the choriocapillaris, the rich vascular bed that is adjacent to the other side of the Bruch ...