Type I angiotensin II receptor (AT1R) plays a role in the regulation of epithelial Na + channel activity in the distal convoluted tubule but it is less important in the cortical collecting duct.

It is caused by mutations in the SLC12A3 gene, which encodes the sodium chloride cotransporter in the distal convoluted tubule. 8 Gitelman syndrome usually presents in adolescence and adulthood with ...

This phenomenon is explained, at least in part, by the interaction between salt reabsorption in the distal convoluted tubule (DCT) and potassium secretion in the connecting tubule/collecting duct of ...

We evaluated treatment outcomes and histological factors in patients with distal bile duct carcinoma. Seventy-four cases of resection of carcinoma of the distal bile ducts treated at our department ...

Moreover, transcriptomic studies have confirmed the differences between urothelial carcinoma and cdRCC, the possible true origin of this disease in the distal convoluted tubule (DCT), differentiating ...

Included in this analysis are trials in which preterm infants with or developing CLD and at least five days of age were randomly allocated to receive a diuretic acting on the distal renal tubule.

Schematic representation of the nephron and active transport mechanisms in the proximal tubule. (a) A schematic figure showing all segments of the nephron: Bowman’s capsule, proximal tubule, loop of ...

We recently demonstrated that BAR3 is expressed in most of the nephron segments also expressing the type-2 vasopressin receptor (AVPR2), including the thick ascending limb (TAL) of Henle, the distal ...

Bile duct stones, which form from cholesterol or bile pigments, can block the bile ducts. Difficult-to-treat bile duct stones are defined by their diameter (above 15 mm), number, unusual shape (such ...