Mechano-Growth Factor (MGF), often referred to as the IGF-1 Ec isoform (or IGF-1 Eb), is a splice variant of the insulin-like ...

Calcium (Ca2+) drives many cellular functions, though the way it controls quality of proteins in the endoplasmic reticulum ...

Tesamorelin is a synthetic 44–amino acid analog of growth hormone–releasing hormone (GHRH) that has attracted attention outside the experimental domain for its potential as a research tool. This ...

Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...

1Department and Graduate Institute of Pharmacology, College of Medicine, National Taiwan University, Taipei, Taiwan, R.O.C., Taipei, Taiwan.

A man with type 1 diabetes has become the first patient to produce his own insulin after receiving genetically engineered cell transplants, without needing drugs to prevent rejection. The case, ...

Insulin signaling under normal physiological conditions as well as its disruption in response to oxidative stress represents a field of intense research interest. It is generally accepted that insulin ...

To continue reading this content, please enable JavaScript in your browser settings and refresh this page. Preview this article 1 min AKT Development Corp. has made a ...

Trump officials have come under fire for using the app to discuss war plans. As the White House comes under fire for allegedly using Signal to discuss sensitive foreign policy plans, the encrypted ...

Adrenomedullin disrupts insulin signaling in blood vessels, leading to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study by a team at the Max Planck Institute ...

After slashing the U.S. prices of several of its insulin products by 75% at the start of 2024, Novo Nordisk is ending the year by announcing similar price reductions for most of its other insulins for ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...