Marcotrigiano (from left), Rice, Dentzer, and Lorenz, posing with Sadie the black lab, found some surprises in the structure of hepatitis C virus's NS2-3 protease.

The team presented the three-dimensional structure of SENP5 in complex with different types of SUMO. The results of the analysis of the different complexes reveal a positively charged region that ...

Some of the mystery has been solved with the publication last month of the first high-resolution crystal structure of an intramembrane protease. Yongchen Wang, Yingjiu Zhang, and Ya Ha from Yale ...

Among Atg4-family proteases, crystallographic studies have been limited to Homo sapiens (Hs) Atg4A and HsAtg4B. The first reported structure was HsAtg4B, whose structure is composed of the two ...

Figure 1: Overall structure of serpin-protease complex and comparison with other serpins. Figure 2: Stereo diagram showing the RCL between P4 and P4′ in the electron density and interactions ...

Crystal structure of SARS-CoV-2 main protease (Mpro) in complex with a Chinese herb inhibitor shikonin. a Chemical structure of the non-colavent inhibitor shikonin. b Structure of Mpro dimer.

A research led by the IBB-UAB has managed to decypher the structure of the human protease SENP5, implicated in neurodegenerative disorders, cardiovascular diseases and the development of cancer.

Crystal structure of SARS-CoV-2 papain-like protease. Compuscript Ltd. Journal Acta Pharmaceutica Sinica B DOI 10.1016/j.apsb.2020.08.014 ...

Foldit players demonstrate that human spatial awareness can outsmart computers in modeling simian AIDS-causing virus. It took the online gaming community just three weeks to solve the structure of ...

Researchers have performed the first room temperature X-ray measurements on the SARS-CoV-2 main protease ... X-rays size up protein structure at the 'heart' of COVID-19 virus Date: June 25, 2020 ...

Get Instant Summarized Text (Gist) The three-dimensional structure of the human protease SENP5, involved in post-translational SUMOylation, has been determined in complex with various SUMO types.