A research led by the IBB-UAB has managed to decypher the structure of the human protease SENP5, implicated in neurodegenerative disorders, cardiovascular diseases and the development of cancer.

A research led by the IBB-UAB has managed to decypher the structure of the human protease SENP5, implicated in neurodegenerative disorders, cardiovascular diseases and the development of cancer ...

Inside each cell of the human body are proteins that control which genes are expressed at the right place and time. However, ...

Researchers have identified a protein–protease duo essential to the mobilization of the immune system against helminth infection.

Far from being simple degradative enzymes, proteases are now seen as key signalling molecules and desirable drug targets in several diseases. Turk discusses our success so far at targeting ...

FtsH Protease: An ATP-dependent, membrane-embedded metalloprotease that plays a critical role in quality control by targeting and degrading compromised thylakoid proteins.

In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be ...

A predictive biophysical model that integrates protein-DNA structures and sequences to accurately determine genomic binding sites and affinities of DNA-binding proteins.

Abstract Summary Pharmacological enhancement of endoplasmic reticulum (ER) proteostasis is an attractive strategy to mitigate pathology linked to etiologically-diverse protein misfolding diseases.

Rates of the Powassan virus infections — which can cause seizures and paralysis — are increasing across North America. Researchers from Penn State, the University of Minnesota and the US Department of ...

The human muscular system is complex and has many functions in the body, like mobility and stability. Learn more about the muscular system here.