Crystal structure of SARS-CoV-2 main protease (Mpro) in complex with a Chinese herb inhibitor shikonin. a Chemical structure of the non-colavent inhibitor shikonin. b Structure of Mpro dimer.

Figure 1: Overall structure of serpin-protease complex and comparison with other serpins. Figure 2: Stereo diagram showing the RCL between P4 and P4′ in the electron density and interactions ...

XMRV is a retrovirus that has been linked to prostate cancer and chronic fatigue syndrome. The crystal structure of the XMRV protease differs from the structures of other retropepsins and instead ...

Some of the mystery has been solved with the publication last month of the first high-resolution crystal structure of an intramembrane protease. Yongchen Wang, Yingjiu Zhang, and Ya Ha from Yale ...

Marcotrigiano (from left), Rice, Dentzer, and Lorenz, posing with Sadie the black lab, found some surprises in the structure of hepatitis C virus's NS2-3 protease.

Researchers have performed the first room temperature X-ray measurements on the SARS-CoV-2 main protease ... X-rays size up protein structure at the 'heart' of COVID-19 virus Date: June 25, 2020 ...

The team presented the three-dimensional structure of SENP5 in complex with different types of SUMO. The results of the analysis of the different complexes reveal a positively charged region that ...

A research led by the IBB-UAB has managed to decypher the structure of the human protease SENP5, implicated in neurodegenerative disorders, cardiovascular diseases and the development of cancer.

Researchers have performed the first room temperature X-ray measurements on the SARS-CoV-2 main protease -- the enzyme that enables the virus to reproduce. It marks an important first step in the ...

Get Instant Summarized Text (Gist) The three-dimensional structure of the human protease SENP5, involved in post-translational SUMOylation, has been determined in complex with various SUMO types.