The pivotal point of vertebrate sex determination is the development of the gonad into a testis or ovary, which governs phenotypic sex through the production of hormones. The identification of Sry ...

Cambridge scientists have identified an ‘on/off’ switch in a type of cancer which typically occurs in the testes and ovaries called ‘malignant germ cell tumours’. The research was published today, 01 ...

When Sry, the testis determining gene, was identified in the early nineties, it was hoped that the other main players involved in the choice of making testes or ovaries would rapidly emerge.