Summary: New research uncovers how tau pathology spreads and damages synapses in progressive supranuclear palsy (PSP). Using ...

Motor neurone disease (MND) is a rare but progressive neurological disorder characterised by the degeneration of motor ...

This study identifies astrocyte-intrinsic mechanisms by which the LRRK2 G2019S, a mutation linked to familial Parkinson's disease, disrupts synaptic integrity in the anterior cingulate cortex. The ...

Glial cells support neurological structures, function, cognition, behaviours, physical skills, and motor coordination.

AI Unveils Key Role of Astrocytes in Brain Function Florida Atlantic University Long overlooked and underestimated, glial cells - non-neuronal cells that support, protect and communicate with neurons ...

As a neuromodulator, norepinephrine is a powerful force in the brain. We all know it orchestrates rapid changes in behavior such as the fight-or-flight response. Fewer people know that astrocytes ...

Astrocytes also send out many thin tentacles, known as processes, which can each wrap around a single synapse—the junctions where two neurons interact with each other—to create a tripartite ...

eLife Assessment This fundamental study examines whether synaptic cell adhesion molecules neuroligin 1-3 resident on astrocytes, rather than neurons, exert effect on synaptic structure and function.

The synapse elimination activity of astrocytes in AD is induced via their interaction with C1q, an innate immune protein that is an initiator of the classical complement cascade at synapses (24). C1q ...

Synapses are small gaps between neurons through which signals are transmitted. This transmission of signals is what allows ...

Astrocytes play diverse roles in the brain such as supporting the functions of neurons, participating in synapse formation and function, releasing neurotransmitters and making the blood-brain barrier.