The San Francisco 49ers will be without their starting quarterback and their best defensive player when they visit the Green ...

The San Francisco 49ers fell to 5-6 on the season in losing to the Green Bay Packers on Sunday. Top takeaways with Brock ...

The San Francisco 49ers will be missing two of their best players in their must-win matchup against the Green Bay Packers ...

San Francisco 49ers quarterback Brock Purdy is out for Week 12's matchup with the Green Bay Packers. Defensive end Nick Bosa ...

Big news and not good news out of the Bay Area on Friday. The 5-5 San Francisco 49ers will be in Green Bay on Sunday to play ...

Jaire Alexander, Edgerrin Cooper, Brock Purdy and Nick Bosa were all ruled out Friday; 49ers LT Trent Williams joins them on ...

San Francisco 49ers quarterback Brock Purdy (13) celebrates after scoring a touchdown with guard Aaron Banks, left, and guard ...

The 49ers have ruled out quarterback Brock Purdy for Sunday’s game against the Packers. It appeared to be trending that way ...

Ten games into their season, the San Francisco 49ers wound up back at .500 for the fifth time as their schedule moves into an ...

San Francisco 49ers quarterback Brock Purdy will miss Sunday's game against the Green Bay Packers with a sore throwing ...

This just isn't the 49ers' week. They have now been dealt the worst-case scenario with Nick Bosa's status against the Packers ...

LB Fred Warner, WR Deebo Samuel Sr., RB Christian McCaffrey and DL Nick Bosa identified key areas for improvement as the team ...