BMJ

Carbon footprint of industry-sponsored late-stage clinical trials

Objectives To quantify the carbon footprint from a sample of pharma industry sponsored phase III trials. To develop an approach that can readily be applied to future trials by AstraZeneca and other ...
BMJ Open

Ethics and dilemmas regarding acceptance of COVID-19 vaccine among people living in an Indian metropolitan city during the pandemic: a qualitative study

Objectives To explore public perceptions of COVID-19 vaccine acceptance and hesitancy in India, and to identify underlying factors influencing attitudes toward vaccination during the second wave of ...
BMJ

Controlling Nutritional Status (CONUT) score as a predictor of all-cause mortality in elderly hypertensive patients: a prospective follow-up study

Objectives The aim of this study was to elucidate the impact of nutritional status on survival per Controlling Nutritional Status (CONUT) score and Geriatric Nutritional Risk Index (GNRI) in patients ...
BMJ Open

Using virtual twin-based AI models to detect atrial fibrillation and improve stroke outcomes [TAILOR]: a multicentre prospective cohort study

Introduction Atrial fibrillation (AF) is the leading cause of cardioembolic stroke and is associated with increased stroke severity and fatality. Early identification of AF is essential for adequate ...
BMJ Open

Clinical characteristics and outcomes of patients with type 2 diabetes mellitus and chronic kidney disease from two new-user medication cohorts: a retrospective cohort study ...

Objectives Given the rapidly evolving therapeutic landscape for type 2 diabetes (T2D) and chronic kidney disease (CKD), this study aimed to characterise the clinical profiles and real-world outcomes ...
BMJ Open

A protocol for a rapid realist policy review (RRPR) of the impact of social determinants on self-harm and suicidal thoughts and behaviours in England

Introduction Self-harm and suicidal thoughts and behaviours are a significant public health concern. While individual risk factors have been widely studied, the role of social determinants in shaping ...
BMJ

Coenzyme Q10 supplementation for prophylaxis in adult patients with migraine—a meta-analysis

Objective To determine the effects of coenzyme Q10 (CoQ10) for reduction in the severity, frequency of migraine attacks and duration of headache in adult patients with migraine. Design Systematic ...
BMJ

Premenstrual syndrome and alcohol consumption: a systematic review and meta-analysis

Objective Premenstrual syndrome (PMS) is a very common disorder worldwide which carries an important economic burden. We conducted a systematic review and a meta-analysis to assess the role of alcohol ...
BMJ Open

Randomised trial protocol to assess efficacy of modified olfactory training method for patients with postinfectious olfactory dysfunction

Introduction This article outlines the research protocol for a multicentre, randomised, controlled study designed to evaluate the therapeutic effect of a modified olfactory training (MOT) based on ...
BMJ Open

Risk factors for cancer among the working population in China: a cross-sectional analysis of baseline data from the WECAN project

Objective This study aims to assess the prevalence of cancer risk factors in China’s working population and provide evidence for formulating more targeted workplace cancer prevention strategies.
BMJ Open

Site-randomised trial of a multilevel digital intervention to reduce maternal morbidity and mortality: a study protocol

Introduction Compared with other high-income countries, the USA continues to have the highest rates of pregnancy-related and associated mortality and morbidity (PRAMM), particularly in rural areas and ...
BMJ

Factors associated with breastfeeding in England: an analysis by primary care trust

1 Policy Research Unit in Maternal Health and Care, National Perinatal Epidemiology Unit, University of Oxford, Oxford, UK 2 Mother and Infant Research Unit, College of Medicine, Dentistry and Nursing ...