Defect centers have been used to demonstrate a wide range of functionalities (1–5), including remote entanglement (), control of large nuclear spin clusters (), and quantum sensing of local ...

We demonstrate that substitutionally inert octahedral metal complexes, such as the iridium(III) carbene complex (1a), provide a useful source of potent inhibitors for unexplored oncogenic protein ...

Rapid pathogen detection is crucial for effective disease management, particularly in bloodstream infections. Current molecular diagnostics often require nucleic acid preamplification, adding time and ...

Land use change is crucial to addressing the existential threats of climate change and biodiversity loss while enhancing food security [M. Zurek et al., Science 376, 1416–1421 (2022)].The ...

Turbulence at centimeter scales plays a pivotal role in shaping the overturning circulation of the deep ocean (1, 2), as well as the ocean’s capacity to distribute and store climate-critical tracers ...

HBx plays a pivotal role in HBV replication by enhancing cccDNA transcription. However, the HBx structure remains unsolved, representing a significant gap in knowledge. Here, we show the cryo-EM ...

During oogenesis, maternally derived protein/mRNA (e.g. Oskar, Vasa, Aubergine, Tudor) localize to the posterior pole for the formation of the germ plasm which possess the ability to induce primordial ...

High-resistant starch (RS)/low-glutelin sbeIIb/Lgc1 lines were generated by CRISPR-Cas9-induced site-specific mutations in SBEIIb in an elite low-glutelin japonica rice cultivar ().According to this ...

Green pigmentation provides a wide variety of animals with the ability to camouflage themselves among green vegetation. The molecular mechanisms of green coloration in insects are not well-understood, ...

To better understand the potential health threats and underlying visual pathways of long-term light at night (LAN) exposure, we adopted a widely accepted diurnal animal model tree shrew (Tupaia ...

Nav1.8 sodium channels are highly expressed in primary pain-sensing neurons. Suzetrigine is a potent and highly selective Nav1.8 inhibitor that has recently been approved by the Food and Drug ...

In this study, we utilized an emerging tubulogenesis model in the ascidian notochord (12, 29, 30), in which lumen pockets first appeared between pairs of notochord cells and then coalesced into a ...