The complement system is a group of proteins that help your immune system to fight infection, heal injury and kill bacteria and viruses.

The complement system is made up of a large number of distinct plasma proteins that react with one another to opsonize pathogens and induce a series of inflammatory responses that help to fight infection.

Mar 12, 2025 · complement, in immunology, a complex system comprising a large number of proteins that act in concert to help eliminate infectious microorganisms. Specifically, the complement system causes the lysis (bursting) of foreign and infected cells, the phagocytosis (ingestion) of foreign particles and cell debris, and the inflammation of surrounding ...

The complement system, also known as complement cascade, is a part of the humoral, innate immune system and enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promote inflammation, and attack the pathogen 's cell membrane. [1]

Jul 18, 2013 · The complement system (CS) is one of the first lines of innate immune defense and plays an important role in the homeostasis of adaptive immunity response. In humans, it was identified as the heat-labile component of serum that assists, or complements, the action of antibodies which are in charge of killing bacteria.

In this review we focus on the extrahepatic complement production and more specifically complement proteins expressed and/or secreted by various human immune cells and discuss its functional implications.

Dec 15, 2009 · Activation of complement leads to robust and efficient proteolytic cascades, which terminate in opsonization and lysis of the pathogen as well as in the generation of the classical...

Feb 14, 2023 · The complement system is made up of approximately 40 proteins of an enzymatic, receptor, and regulatory nature, which all participate in a very well-functioning immune system.

The complement system is an enzyme cascade that helps defend against infection via activation of a local inflammatory response. Many complement proteins occur in serum as inactive enzyme precursors (zymogens); others reside on cell surfaces. …

Complement was discovered by Jules Bordet as a heat-labile component of normal plasma that causes the opsonisation and killing of bacteria. The complement system refers to a series of >20 proteins, circulating in the blood and tissue fluids.